You can create different groups with different blocking settings with IMLock Enterprise.  It is very easy to do.

1. Open Administrator

2. Create settings for the first profile

3. Export to the appropriate directory/URL.

4. Change the settings for the second profile

5. Export to the appropriate directory/URL

6. Repeat

Network Share Example:

Profile 1 = G://imlockshare/profile1/iml.xml

Profile 2 = G://imlockshare/profile2/iml.xml

Profile 3 = G://imlockshare/profile3/iml.xml

You can add as many as you want.

Internet Share Example:

Profile 1 = http://www.imlockshare.com/profile1/iml.xml

Profile 2 = http://www.imlockshare.com/profile2/iml.xml

Profile3 = http://www.imlockshare.com/profile3/iml.xml

Again, there is no limit to the number of profiles.